Daily oral doses (400 mg/kg.b.wt.) of the lyophilized aqueous extract of C. verbascifolia were given to adult Wistar rats for a period of 4 weeks. The results revealed a significant decrease in cholesterol level (P<0.05) and inorganic phosphorus (P < 0.001), in addition to a marked increase (P < 0.001) in serum albumin and calcium. The haemogram showed a marked leucocytopenia, lymphocytopenia, decreased neutrophils, monocytes (P < 0.001) and basophils counts (P<0.05). Moreover, a significant increase (P<0.01) in MCH was also recorded. Changes in body and organ weights as well as histopathological findings were also discussed.
Harraz, F., Farah, M., & Abdel-Aziz, S. (1993). SUBCHRONIC EFFECTS OF THE ORAL ADMINISTRATION OF THE LYOPHILIZED AQUEOUS EXTRACT OF CHROZOPHORA VERBASCIFOLIA IN RATS. Zagazig Journal of Pharmaceutical Sciences, 2(1), 161-169. doi: 10.21608/zjps.1993.189000
MLA
Fathalla Harraz; Mohamed Farah; Sayed Abdel-Aziz. "SUBCHRONIC EFFECTS OF THE ORAL ADMINISTRATION OF THE LYOPHILIZED AQUEOUS EXTRACT OF CHROZOPHORA VERBASCIFOLIA IN RATS", Zagazig Journal of Pharmaceutical Sciences, 2, 1, 1993, 161-169. doi: 10.21608/zjps.1993.189000
HARVARD
Harraz, F., Farah, M., Abdel-Aziz, S. (1993). 'SUBCHRONIC EFFECTS OF THE ORAL ADMINISTRATION OF THE LYOPHILIZED AQUEOUS EXTRACT OF CHROZOPHORA VERBASCIFOLIA IN RATS', Zagazig Journal of Pharmaceutical Sciences, 2(1), pp. 161-169. doi: 10.21608/zjps.1993.189000
VANCOUVER
Harraz, F., Farah, M., Abdel-Aziz, S. SUBCHRONIC EFFECTS OF THE ORAL ADMINISTRATION OF THE LYOPHILIZED AQUEOUS EXTRACT OF CHROZOPHORA VERBASCIFOLIA IN RATS. Zagazig Journal of Pharmaceutical Sciences, 1993; 2(1): 161-169. doi: 10.21608/zjps.1993.189000