SYNTHESIS OF 3 - SUBSTITUTED ( 6 - BROMO-2- IMIDAZO[4,5-B] PYRIDINYL) PROPIONIC ACID AS ANTIINFLAMMATORY, ANALGESIC, AND ANTIPYRETIC AGENTS

Document Type : Original Article

Authors

1 Pharmaceutical Chemistry Department, Faculty of Pharmacy, Cairo University, Egypt

2 FACULTY OF PHARMACY, CAIRO UNIVERSITY

3 Pharmaceutical Chemistry Department, Faculty of Pharmacy, Zagazig University, Egypt

4 Department of Medicinal Chemistry, Faculty of Pharmacy, Zagazige University, Zagazig, Egypt

5 Medicinal Chemistry Department, Faculty of Pharmacy, University of Zagazig, Zagazig, Egypt

Abstract

A series of 3- substituted (6-bromo - 2 - imidazo  4,5 - b -pyridinyl ) propionic acid hydrazide ( I), thiosemicarbazide ( II) and 1,2,4 - triaołes ( III ) were prepared. Some of the prepared compounds were tested for their antiinflammatory, analgesic and antipyretic activities.

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