PHYTOCHEMICAL INVESTIGATION OF CENTAUREA ARANEOSA GROWING IN EGYPT.

Farrag, Nawal; Abdel-Aziz, Ehsan; El-Domiaty, Maher; El Shafea, Azza

doi:10.21608/zjps.1993.188986

PHYTOCHEMICAL INVESTIGATION OF CENTAUREA ARANEOSA GROWING IN EGYPT.

Document Type : Original Article

Authors

¹ Pharmacognosy Department, Faculty of Pharmacy, University of Zagazig , Zagazig , Egypt

² Department of Pharmacognosy, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.

³ Department of Pharmacognosy, Faculty of Pharmacy, University of Zagazig, Egypt.

⁴ DEPARTMENT OF PHARMACOGNOSY, FACULTY OF PHARMACY UNIVERSITY OF ZAGAZIG , EGYPT.

10.21608/zjps.1993.188986

Abstract

The petroleum ether extract of Centaurea araneosa afforded : Lupeol acetate, long chain acid ( C ₃₀ H₆₀O₂), Lupeol, β- sitosterol- stigmasterol mixture and a waxy substance. The chloroform fraction yielded three methoxylated flavonoid aglycones of rare occurrence in Compositae namely : velutin, hispidulin and cirsmaritin in addition to apigenin. The ethyl acetate fraction yielded β - sitosterol glucoside, apigenin 7-0- glucoside and luteolin 7- 0 - glucoside. Extraction of the sesquiterpene lactones yielded only cnicin. The structure of these compounds was determined through spectral analysis and chemical interconversion as well as comparison with reported data.