Debromination of α- bromoketones can be conducted easily. However, debromination of vinyl bromides is extremely difficult and requires vigorous conditions. This study describes the optimum conditions for the facile debromination of vinyl bromides. A plausible mechanism for the easy debromination is proposed. Also, attempted application of ring contraction of 2-bromocyclohexanediones using Favorskii conditions was unsuccessful.
Al-Sabbagh, O., El-Bermawy, M., EI-Sadek, M., & Al-Ashmawi, M. (1994). OPTIMIZATION AND MECHANISTIC STUDIES OF FACILE DEBROMINATION OF VINYL BROMIDES WITH VICINAL SUBSTITUTED AMINO GROUP RESIDUES. Zagazig Journal of Pharmaceutical Sciences, 3(1), 131-135. doi: 10.21608/zjps.1994.186723
MLA
Osama Al-Sabbagh; Mohamed El-Bermawy; Mohamed EI-Sadek; Mohamed Al-Ashmawi. "OPTIMIZATION AND MECHANISTIC STUDIES OF FACILE DEBROMINATION OF VINYL BROMIDES WITH VICINAL SUBSTITUTED AMINO GROUP RESIDUES", Zagazig Journal of Pharmaceutical Sciences, 3, 1, 1994, 131-135. doi: 10.21608/zjps.1994.186723
HARVARD
Al-Sabbagh, O., El-Bermawy, M., EI-Sadek, M., Al-Ashmawi, M. (1994). 'OPTIMIZATION AND MECHANISTIC STUDIES OF FACILE DEBROMINATION OF VINYL BROMIDES WITH VICINAL SUBSTITUTED AMINO GROUP RESIDUES', Zagazig Journal of Pharmaceutical Sciences, 3(1), pp. 131-135. doi: 10.21608/zjps.1994.186723
VANCOUVER
Al-Sabbagh, O., El-Bermawy, M., EI-Sadek, M., Al-Ashmawi, M. OPTIMIZATION AND MECHANISTIC STUDIES OF FACILE DEBROMINATION OF VINYL BROMIDES WITH VICINAL SUBSTITUTED AMINO GROUP RESIDUES. Zagazig Journal of Pharmaceutical Sciences, 1994; 3(1): 131-135. doi: 10.21608/zjps.1994.186723
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