Manganus chloride (2 mg/kg b.wt.) was given every other day intraperitoneally (i.p.) for a period of 5 weeks to mature male rabbits. Rabbits were challenged with Clostridia antisera as a stress factor. The results indicated significant elevation in the levels of ß and y-globulins (P < 0.001), serum ALT and AST activities (P< 0.01) and significant decrease in the levels of a-globulins and urea (SUN) (P < 0.001). The blood picture was not significantly changed except for eosinophils and monocytes counts which showed a marked increase and decrease (P <0.001) respectively. Whereas, a moderate increase (P < 0.05) was recorded in PO2, O2 SAT% and O2-CT% of the blood. This study represents the hazardous effect of prolonged exposure to manganus chloide in both histotoxic anoxia and liver dysfunction.
Diab, A. (1994). SUBCHRONIC EFFECTS OF INTRAPERITONEAL ADMINISTRATION OF MANGANUS CHLORIDE TO RABBITS. Zagazig Journal of Pharmaceutical Sciences, 3(1), 103-108. doi: 10.21608/zjps.1994.186707
MLA
Abdel-Aziz Diab. "SUBCHRONIC EFFECTS OF INTRAPERITONEAL ADMINISTRATION OF MANGANUS CHLORIDE TO RABBITS", Zagazig Journal of Pharmaceutical Sciences, 3, 1, 1994, 103-108. doi: 10.21608/zjps.1994.186707
HARVARD
Diab, A. (1994). 'SUBCHRONIC EFFECTS OF INTRAPERITONEAL ADMINISTRATION OF MANGANUS CHLORIDE TO RABBITS', Zagazig Journal of Pharmaceutical Sciences, 3(1), pp. 103-108. doi: 10.21608/zjps.1994.186707
VANCOUVER
Diab, A. SUBCHRONIC EFFECTS OF INTRAPERITONEAL ADMINISTRATION OF MANGANUS CHLORIDE TO RABBITS. Zagazig Journal of Pharmaceutical Sciences, 1994; 3(1): 103-108. doi: 10.21608/zjps.1994.186707