Racemic amines 1-phenyl-ethylamine and 1-amino-2-propanol were found to undergo kinetic resolution in the stereoselective reaction with acetanthranil. The residual amines have optical rotation of (+) 5.2° and (+) 4.5° which correspond to optical purity of about 15.7% and 18% for 1-phenylethylamine and 1-amino-2-propanol, respectively. The effect of temperature, reaction time, solvent, concentration of amine and catalyst were examined on the kinetic resolution.
Sharaf El-Din, N. (1994). STEREOSELECTIVE REACTION BETWEEN ACETANTHRANIL AND RACEMIC AMINE. Zagazig Journal of Pharmaceutical Sciences, 3(1), 35-39. doi: 10.21608/zjps.1994.186601
MLA
Nabaweya Sharaf El-Din. "STEREOSELECTIVE REACTION BETWEEN ACETANTHRANIL AND RACEMIC AMINE", Zagazig Journal of Pharmaceutical Sciences, 3, 1, 1994, 35-39. doi: 10.21608/zjps.1994.186601
HARVARD
Sharaf El-Din, N. (1994). 'STEREOSELECTIVE REACTION BETWEEN ACETANTHRANIL AND RACEMIC AMINE', Zagazig Journal of Pharmaceutical Sciences, 3(1), pp. 35-39. doi: 10.21608/zjps.1994.186601
VANCOUVER
Sharaf El-Din, N. STEREOSELECTIVE REACTION BETWEEN ACETANTHRANIL AND RACEMIC AMINE. Zagazig Journal of Pharmaceutical Sciences, 1994; 3(1): 35-39. doi: 10.21608/zjps.1994.186601
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