A simple and accurate method was described for the quantitative determination of mefenamic acid utilizing precipitation reactions with silver (I), copper (II) and iron (III). Mefenamic acid was precipitated from its neutral alcoholic solution by silver nitrate, copper acetate or ferric chloride standard solutions followed by direct determination of the above cited ions in the precipitate or its indirect determination in the filtrate applying atomic absorption spectroscopy. The optimum conditions for precipitation have been carefully studied. The molar ratio of the reactants were ascertained. Statistical analysis of the results obtained compared to the results of the official method revealed equal precision and accuracy. The suggested procedures were applied for determing mefenamic acid in pharmaceutial preparations as well and proved validity.
Salem, H., & Aboul Kheir, A. (1995). ATOMIC ABSORPTION SPECTROMETRY OF ACIDIC PHARMACEUTICAL CONSTITUENTS THROUGH PRECIPITATION BY METAL IONS *: II. DETERMINATION OF MEFENAMIC ACID. Zagazig Journal of Pharmaceutical Sciences, 4(2), 49-56. doi: 10.21608/zjps.1995.185627
MLA
Hesham Salem; Afaf Aboul Kheir. "ATOMIC ABSORPTION SPECTROMETRY OF ACIDIC PHARMACEUTICAL CONSTITUENTS THROUGH PRECIPITATION BY METAL IONS *: II. DETERMINATION OF MEFENAMIC ACID". Zagazig Journal of Pharmaceutical Sciences, 4, 2, 1995, 49-56. doi: 10.21608/zjps.1995.185627
HARVARD
Salem, H., Aboul Kheir, A. (1995). 'ATOMIC ABSORPTION SPECTROMETRY OF ACIDIC PHARMACEUTICAL CONSTITUENTS THROUGH PRECIPITATION BY METAL IONS *: II. DETERMINATION OF MEFENAMIC ACID', Zagazig Journal of Pharmaceutical Sciences, 4(2), pp. 49-56. doi: 10.21608/zjps.1995.185627
VANCOUVER
Salem, H., Aboul Kheir, A. ATOMIC ABSORPTION SPECTROMETRY OF ACIDIC PHARMACEUTICAL CONSTITUENTS THROUGH PRECIPITATION BY METAL IONS *: II. DETERMINATION OF MEFENAMIC ACID. Zagazig Journal of Pharmaceutical Sciences, 1995; 4(2): 49-56. doi: 10.21608/zjps.1995.185627
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