SYNTHESIS OF GUANOSINE--3'- (5- bromo -4- chloro-3 -hyroxyindolyl)- PHOSPHATE(G- 3'- BCIP)

Document Type : Original Article

Author

Institute voor Moleculaire Biologie, Vrije Universiteit Brussel, Paardenstraat 65 Sint - Genesius - Rode - Belgium

Abstract

N²-Benzoyl-5'-0-dimethoxytrityl-2'-O-tetrahydropyranyl guanosine and 1-acetyl-5 -bromo-4-choroindol -3-yl-3-phosphorodichloridate were synthesized and coupled to give, after deprotection and purification, the title compound.