A simple method for the determination of quinidine sulfate in tablets is based on the formation of an ion-pair between quinidine Comand thymol blue (TB) at pH=5.5 in aqueous-methanol solution. The absorbance of the ion-pair formed is measured and the Colncentration of the drug is calculated. The molar ratio of the ion-pair is determined and found to be 2:1 and with general formula [Q]+4 2.[T.B]-1 SO4-2 HSO4-1 as calculated by elemental analysis. Using the present method quinidine sulfate in tablets was assayed. The results were statistically compared with those obtained by the official method.
Metwally, M. (1997). SPECTROPHOTOMETRIC DETERMINATION OF QUINIDINE SULFATE BY ION-PAIR FORMATION. Zagazig Journal of Pharmaceutical Sciences, 6(1), 33-40. doi: 10.21608/zjps.1997.184952
MLA
Mamdouh Metwally. "SPECTROPHOTOMETRIC DETERMINATION OF QUINIDINE SULFATE BY ION-PAIR FORMATION", Zagazig Journal of Pharmaceutical Sciences, 6, 1, 1997, 33-40. doi: 10.21608/zjps.1997.184952
HARVARD
Metwally, M. (1997). 'SPECTROPHOTOMETRIC DETERMINATION OF QUINIDINE SULFATE BY ION-PAIR FORMATION', Zagazig Journal of Pharmaceutical Sciences, 6(1), pp. 33-40. doi: 10.21608/zjps.1997.184952
VANCOUVER
Metwally, M. SPECTROPHOTOMETRIC DETERMINATION OF QUINIDINE SULFATE BY ION-PAIR FORMATION. Zagazig Journal of Pharmaceutical Sciences, 1997; 6(1): 33-40. doi: 10.21608/zjps.1997.184952
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