DITERPENE CONSTITUENTS OF JUNIPERUS POLYCARPOS AND THEIR ANTIMICROBIAL AND ANTI-INFLAMMATORY ACTIVITIES

Document Type : Original Article

Author

School of Pharmacy, Addis Ababa University, Addis Ababa, P.O.Box 1176, Ethiopia .

Abstract

Activity-directed study of Juniperus polycarpos led to the isolation of active antimicrobial viz., hinokiol, sandaracopimaric acid 4-eniabietic acid, and other minor terpenes in addition to sabinic acid. The antiinflammatory activity of hinokiol was also demonstrated, using carrageenan-induced inflammation_in rats. The structures of the isolated terpenes were determined by 1HNMR, 13CNMR and 2DNMR, APT, DEPT, PND spectra.