EFFECT OF ALBENDAZOLE ON SOME HORMONAL, HAEMATOLOGICAL AND BIOCHEMICAL PROFILES IN SHEEP

Amer, Magdy; Mohamed, Gehad; El-Said, Mohamed

doi:10.21608/zjps.1998.184794

EFFECT OF ALBENDAZOLE ON SOME HORMONAL, HAEMATOLOGICAL AND BIOCHEMICAL PROFILES IN SHEEP

Document Type : Original Article

Authors

¹ Department of Pharmacology, Faculty of Veterinary Medicine, University of Mansoura, Egypt.

² Pharmacology Department Faculty of Veterinary Medicine , Mansoura University, Egypt

³ Biochemistry Department Faculty of Veterinary Medicine , Mansoura University, Egypt

10.21608/zjps.1998.184794

Abstract

In this study, the effects of albendazole (10 mg/kg b.wt.) on some hormonal, haematological and biochemical profiles of 20 mature sheep of both sex were studied after its oral administration as 2.5 % suspension. Albendazole exerted a significant increase in the levels of serum globulins, alanine aminotransferase (ALT),aspartate aminotransferase (AST), superoxide dismutase (SOD), total leukocytic count (WBCS) and their differential count, particularly lymphocytes and neutrophils. Moreover, it evoked a significant decrease in serum testosterone of rams. Meanwhile, it demonstrated no significant effect on the levels of estradiol and progesterone in ewes.