A new series of 2,3-dihydro-4(1H)-quinazolinones was synthesized by condensation of 2-methylamino-N-substituted benzamides (III) with either formaldehyde or aromatic aldehydes to produce 2,3-dihydro-1-methyl-3-(substituted phenyl)-4(1H) -quinazolinones (V) and 2,3-dihydro-2,3-di(substituted phenyl)-1-methyl-4(1H)-quinazolinones (VI) respectively. The anti-inflammatory study of some of the prepared compounds revealed that compound (Vla) showed significant activity in comparison with flufenamic acid.
Sakr, S. (2003). Synthesis and Anti-inflammatory Activity of New 2,3-Dihydro-4(1H)-quinazolinone Derivatives. Zagazig Journal of Pharmaceutical Sciences, 12(1), 24-28. doi: 10.21608/zjps.2003.178067
MLA
Samy Sakr. "Synthesis and Anti-inflammatory Activity of New 2,3-Dihydro-4(1H)-quinazolinone Derivatives". Zagazig Journal of Pharmaceutical Sciences, 12, 1, 2003, 24-28. doi: 10.21608/zjps.2003.178067
HARVARD
Sakr, S. (2003). 'Synthesis and Anti-inflammatory Activity of New 2,3-Dihydro-4(1H)-quinazolinone Derivatives', Zagazig Journal of Pharmaceutical Sciences, 12(1), pp. 24-28. doi: 10.21608/zjps.2003.178067
VANCOUVER
Sakr, S. Synthesis and Anti-inflammatory Activity of New 2,3-Dihydro-4(1H)-quinazolinone Derivatives. Zagazig Journal of Pharmaceutical Sciences, 2003; 12(1): 24-28. doi: 10.21608/zjps.2003.178067
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