Four isoflavones (glabrisoflavone, prunitin, santal and genisetin), two flavonols (kaempferol and quercetin) and one phenolic acid (4-hydroxy phenyl acetic acid) beside β-sitosterol and ß-sitosterol-O-glucoside, were isolated from the aerial parts of the Egyptian licorice (G. glabra). Santal, 4-hydroxy phenyl acetic acid and B-sitosterol-O-glucoside are reported here for the first time in the genus Glycyrrhiza. The structures of the isolated compounds were determined by IR, UV, MS, 1H-NMR and 13CNMR (2D experiments), as well as comparison with reference samples. Preliminary pharmacological testing of the total alcoholic extract and some of its fractions demonstrated potent anti-inflammatory and hepato-protective activities compared to hydrocortisone and silymarin, respectively.
El-Domiaty, M., Abdel-Aziz, E., El-Shafae, A., & Mohammed, M. (2003). PHENOLIC CONSTITUENTS AND BIOLOGICAL ACTIVITY OF THE AERIAL PARTS OF THE EGYPTIAN LICORICE (GLYCYRRHIZA GLABRA L). Zagazig Journal of Pharmaceutical Sciences, 12(1), 14-23. doi: 10.21608/zjps.2003.178045
MLA
Maher El-Domiaty; Ehsan Abdel-Aziz; Azza El-Shafae; Maged Mohammed. "PHENOLIC CONSTITUENTS AND BIOLOGICAL ACTIVITY OF THE AERIAL PARTS OF THE EGYPTIAN LICORICE (GLYCYRRHIZA GLABRA L)", Zagazig Journal of Pharmaceutical Sciences, 12, 1, 2003, 14-23. doi: 10.21608/zjps.2003.178045
HARVARD
El-Domiaty, M., Abdel-Aziz, E., El-Shafae, A., Mohammed, M. (2003). 'PHENOLIC CONSTITUENTS AND BIOLOGICAL ACTIVITY OF THE AERIAL PARTS OF THE EGYPTIAN LICORICE (GLYCYRRHIZA GLABRA L)', Zagazig Journal of Pharmaceutical Sciences, 12(1), pp. 14-23. doi: 10.21608/zjps.2003.178045
VANCOUVER
El-Domiaty, M., Abdel-Aziz, E., El-Shafae, A., Mohammed, M. PHENOLIC CONSTITUENTS AND BIOLOGICAL ACTIVITY OF THE AERIAL PARTS OF THE EGYPTIAN LICORICE (GLYCYRRHIZA GLABRA L). Zagazig Journal of Pharmaceutical Sciences, 2003; 12(1): 14-23. doi: 10.21608/zjps.2003.178045
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