Adult male Wistar rats were given daily oral doses of the lyophilized aqueous extract of Calligonum comosum at the rate of 400 mg/kg (b.wt.) for 4 weeks. The biochemical changes included a significant increase in the levels of serum Calcium and SUN (P < 0.05). On the other hand, decreased values were noted in the levels of serum albumin (P < 0.01). Haematological changes showed increased lymphocyte count (P < 0.05), whereas, decreases were noted in the levels of Hb (P < 0.01) and total WBCS count (P < 0.05), in addition to panleucocylopenia (P < 0.05) involving all the granulocytes and the monocytes ( P < 0.001).
Harraz, F., Farah, M., & Abdel-Aziz, S. (1993). TOXICOLOGICAL EFFECTS OF THE ORAL ADMINISTRATION OF THE AQUEOUS EXTRACT FROM CALLIGONUM COMOSUM TO RATS. Zagazig Journal of Pharmaceutical Sciences, 2(2), 1-9. doi: 10.21608/zjps.1993.169727
MLA
Fathalla Harraz; Mohamed Farah; Sayed Abdel-Aziz. "TOXICOLOGICAL EFFECTS OF THE ORAL ADMINISTRATION OF THE AQUEOUS EXTRACT FROM CALLIGONUM COMOSUM TO RATS", Zagazig Journal of Pharmaceutical Sciences, 2, 2, 1993, 1-9. doi: 10.21608/zjps.1993.169727
HARVARD
Harraz, F., Farah, M., Abdel-Aziz, S. (1993). 'TOXICOLOGICAL EFFECTS OF THE ORAL ADMINISTRATION OF THE AQUEOUS EXTRACT FROM CALLIGONUM COMOSUM TO RATS', Zagazig Journal of Pharmaceutical Sciences, 2(2), pp. 1-9. doi: 10.21608/zjps.1993.169727
VANCOUVER
Harraz, F., Farah, M., Abdel-Aziz, S. TOXICOLOGICAL EFFECTS OF THE ORAL ADMINISTRATION OF THE AQUEOUS EXTRACT FROM CALLIGONUM COMOSUM TO RATS. Zagazig Journal of Pharmaceutical Sciences, 1993; 2(2): 1-9. doi: 10.21608/zjps.1993.169727