SYNTHESIS OF SOME SUBSTITUTED ACRIDINE DERIVATIVES OF ANTICIPATED ANTICANCER ACTIVITY

Document Type : Original Article

Authors

Pharmaceutical Chemistry Department, faculty of Pharmacy, Cairo University, Cairo, Egypt

Abstract

In the present investigation four series of new acridine derivatives of anticipated antitumor activity have been Synthesized. The first series belongs to 9-phenylimino-acridine-10-acetate derivatives. The second and third series comprise 9-phenylimino-acridine-10-carboxamide derivatives, while the last one includes 9-oxo- acridine-10-carboxamide derivatives of different substitution pattern.