Pharmacognostical studies on zizyphus lotus (L.) Lam; was carried out to identify and differentiate the plant organs. Phytochemical screening revealed that the plant rich with carbohydrates and/or glycosides, volatile substances, saponins, flavonoids, phenolics, steroids and/or triterpenes, and alkaloids and/or nitrogenous bases. The biological studies showed that 70% alcohol extract had promising antimicrobial activity. By examination of the LD50 and analgesic effect after oral administration of various doses of extract 100, 200 and 300 mg/kg body weight, the LD50 of 70% alcohol extract of Zizyphus lotus L. (Lam ) is 12.88 g /kg (mice) with confidence limit of 10.75 g /kg (mice) and 15.44 g /kg (mice). All tested extracts showed significant analgesic activity in all times of experiments except at 20 min. In conclusion.the tested extract can be used safely for analgesic purposes.
Farah, H., Al- Atoom, A., Shehab, G., & Abd El-wahab, M. (2011). PHARMACOGNOSTIC AND BIOLOGICAL EVALUATIONS OF ZIZYPHUS LOTTS (L.) LAM. LEAVES AND STEMS, GROWING IN EGYPT.. Zagazig Journal of Pharmaceutical Sciences, 20(2), 24-36. doi: 10.21608/zjps.2011.167360
MLA
Husni Farah; Ali Al- Atoom; Gaber Shehab; Mohammed Abd El-wahab. "PHARMACOGNOSTIC AND BIOLOGICAL EVALUATIONS OF ZIZYPHUS LOTTS (L.) LAM. LEAVES AND STEMS, GROWING IN EGYPT.", Zagazig Journal of Pharmaceutical Sciences, 20, 2, 2011, 24-36. doi: 10.21608/zjps.2011.167360
HARVARD
Farah, H., Al- Atoom, A., Shehab, G., Abd El-wahab, M. (2011). 'PHARMACOGNOSTIC AND BIOLOGICAL EVALUATIONS OF ZIZYPHUS LOTTS (L.) LAM. LEAVES AND STEMS, GROWING IN EGYPT.', Zagazig Journal of Pharmaceutical Sciences, 20(2), pp. 24-36. doi: 10.21608/zjps.2011.167360
VANCOUVER
Farah, H., Al- Atoom, A., Shehab, G., Abd El-wahab, M. PHARMACOGNOSTIC AND BIOLOGICAL EVALUATIONS OF ZIZYPHUS LOTTS (L.) LAM. LEAVES AND STEMS, GROWING IN EGYPT.. Zagazig Journal of Pharmaceutical Sciences, 2011; 20(2): 24-36. doi: 10.21608/zjps.2011.167360